12+ weeks

[Sleepwalker]

1. I ordered LgG testing @ 18 days post exposure and then again at 12 weeks. Initial results were: 3.25, 12 week: 3.91. This looks definitive from what I’ve read here. Given no lesions or apparent symptoms, does my score trend look like a new or pre-existing infection?

2. If I fail to have a noticeable primary outbreak after 20 days, but test positive via LgG, Am I still at risk of having a severe primary outbreak? My assumption is that test indicates I have some protection now due to having antibodies and that it’s lack of antibodies that cause severe primary outbreak.

[Terri Warren]

The index value of 3.25 would have been in what we call the lower positive range. The Centers for Disease Control recommends that anyone who acquires and index value of less than 3.5 obtain confirmatory testing.It is unlikely that you were infected 18 days before this test Was done. Your index value of 3.91 as above the 3.5 but if you have had no symptoms, I think a confirmatory test would be useful. I recently had someone with an index value of 12 not confirm by Western blot. It is generally correct that the absence of antibody is what causes a severe outbreak but if someone has HSV one prior to acquiring HSV-2, that antibody offers enough modulation Of symptoms that sometimesAnd outbreak can go unnoticed

Terri

[Sleepwalker]

Hi it’s been almost 11 months since possible exposure.

1) To the best of my knowledge, I have had no lesions.

2) My original test scores 3.25 and 3.91 were through Quest. I have retaken another igg test through labcorp returning a 2.83 with a positive Supplementary test. Full Results are as follows:

HSV-2 Type Spec Ab, IgG w/Rflx
Result: 2.83
Flag High
HSV-2 IgG Supplemental Test
Result: Positive
Flag: ABNORMAL

Given these results, would you advise a western blot? Though I don’t have lesions — I do have sporadic itchness / burning feeling from groin area. It does seem to resolve using anti-fungal cream, but it also comes back frequently… I also wonder how much of this is anxiety…

Also — why would the Supplemental Test be flagged as “Abnormal”

Any advice would be appreciated — Drs have been a mixed bag…

Thanks

[Terri Warren]

Yes, you need a western blot. Absolutely no question about it. If you chose not to do it, you should consider yourself infected.
Quest has their own confirmatory result which may or may not be accurate. It is called an inhibition assay.

Terri

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