April 19, 2020 at 12:15 pm #69956
Here’s my timeline:
Antibody blood test in 2018, sexually inactive for years prior. Results came back negative for everything.
Two months after the antibody test, became sexually actively with a man who also tested negative two months prior and was also sexually inactive for at least a year.
We have been together in a monogamous relationship with each other since 2018 when we both tested negative.
Two weeks ago, I had an HSV-2 outbreak that tested positive via a swab culture.
How is this possible? Is it possible that I had the virus so dormant for many years that it didn’t show up in my blood work two years ago?
April 19, 2020 at 12:18 pm #69959
The IgG test misses 8% of HSV 2 infections, compared to the gold standard western blot
So either one of you has had sex with someone else since the last test or more likely, of your tests missed an HSV 2 infection.
What was the outbreak like for you?
April 19, 2020 at 12:33 pm #69966
Neither one of us has had sex with anyone else since the last test. We’ve only been with each other since that last test.
The outbreak was a small cluster of sores on the lower external labia. My doc says it looks like a recurrent one. I might have had an outbreak last year when I had yeast infection and bv (never had YI nor BV in my life until then), and I was swabbed on the sores they thought might be abrasions caused by the yeast. The swab came back negative at the time. I’m assuming it missed the virus as it might have been healing at that point?
So I’ve had two negative tests in the past: blood work done when I was asymptomatic, and then that swab that was done when sores might have been healing? This time the swab was positive because the timing was right?
Is it possible for the virus to lay dormant and be missed in all these years? Perhaps I got it from someone I’ve been with in my 20s? (I’m in my 40s now).
April 19, 2020 at 12:37 pm #69968
It is definitely possible that you’ve been infected for many years OR you have HSV 1 and that antibody kept a new HSV 2 infection well under control, looking like a recurrence. The IgG test also misses 30% of HSV 1 infections, so this could be the case for either of you.
If both of you waited at least 12 weeks after having sex with anyone else before you did the IgG tests, then the test missed HSV 2 in one of you.
April 19, 2020 at 1:08 pm #69974
Neither one of us had any HSV-1 symptoms show up at any point in our lives. Is is possible to have that virus without symptoms at all?
Can you kindly clarify your last statement? If we waited at least 12 weeks before getting tested after being with someone, the hsv2 could have been missed? Isn’t that the time when the antibodies are supposed to show up?
Lastly, if we both had it previously asymptomatically, is it possible for the virus to lay dormant for so many years?
April 29, 2020 at 1:44 pm #70035
It is possible and common to be infected with either HSV 1 or HSV 2 and not have symptoms, correct.
I’m saying that if you both waited 12 weeks after having sex with anyone else to be tested, but you are swab test positive for HSV 2, then the IgG test missed either the infection in you or the infection in your partner. Yes, the best time to test is 12 weeks after a potentially infectious encounter but the test isn’t perfect – it misses 8% of infections. So someone could be infected and have a negative IgG result – is that a bit clearer?
And yes, the virus can lay dormant for many many years
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