July 1, 2019 at 1:16 pm #40007
I’m a 39f, uncertain about my test results and looking for guidance on retesting. Here’s my timeline:
Late Mar 2019 – tested full STI, HSV. Results negative for everything: HSV 1, 2, all STIs. Started birth control (nuvaring).
A week later – possible exposure
Early Apr 2019 – 1 day after sex started feeling sick. 2 days after develop bad sore throat (puss), flu like symptoms but no fever. Tested negative for strep. Took ZPack, no relief. Took about 10 days to clear. Also got first round of vaccines (Gardasil and Hep B).
Early May 2019 – test for HSV (4 weeks since sex), positive for HSV1 (IGG 25, IGM negative or <1.1), negative for HSV2 and all other STIs.
Question: I read in this article that vaccinations and birth control can affect bloodwork. Here’s the link: https://www.uofmhealth.org/health-library/hw41342#hw41355
Q1: Is it possible that this could have caused my high IGG count? I haven’t had any symptoms outside of that sore throat. The month before I was negative, would HSV show up in just 4 weeks with a count that high (25 Igg)?
Q2: I still have one more round of vaccines. The article says not to test within 6 months of shots…do you recommend I wait this long? That means almost a year I’d have to wait (6 months for three rounds of shots plus 6 month wait period for retest).
Q3: if I retest should I just do an IGG blood test or Western Blot.
July 4, 2019 at 3:55 pm #40758
You don’t mention if you were the giver of oral sex to someone or kissed them. If you did, then I would definitely lean toward you having a new oral infection. I am not aware of any evidence that an HPV vaccine would cause antibody to HSV to appear. And birth control pills would have no impact.
Can you tell me more about the possible exposure experience?
- This reply was modified 6 months, 2 weeks ago by Terri Warren.
July 5, 2019 at 9:06 am #40889
We had kissed a lot when I tested negative in March. There was more kissing and oral in April and then I tested positive in June (4 weeks after oral and sore throat). I’m confused because if it’s a new infection, it seems odd that my igg was quite high but igm was negative? That’s why I was wondering if vaccines and new birth control affected the count? Since the sore throat I’ve had no other symptoms.
July 7, 2019 at 7:02 am #40968
Did the same lab do both tests? I ask because different labs use different test kits and can have different results. If the same lab did both tests, I think it is very likely that you acquired HSV 1 between the negative test and the positive test. It is also possible that the first test missed a long standing HSV 1 infection and the second one picked it up. The IgG test for HSV 1 misses 30% of infection compared to the gold standard western blot. The IgM is irrelevant – the test is poor, it shows up with recurrences, many false positives and of course false negatives. I think it is almost criminal that large labs still offer it.
September 2, 2019 at 5:41 am #48838
Hi Teri, thank you for your response so far. I have an update and follow up question for you.
I retested last week (two months from last testing), same lab (LabCorp) and my IGG level went from 25 to 21. I’m still asymptomatic. IGM still negative. Is there any significance here on the decreasing IGG level? If it’s an old infection, wouldn’t the IGG slowly be increasing?
I got more clarity from my doctor during my retest. She said she had tested me for HSV in April (during my pap) but not via bloodwork. I thought I had been tested years before, but also found out nope, no HSV testing done then either. I thought it would be routine for pregnancy and child births but I guess not. I guess I could have gotten HSV at any time since I no longer know the last time I was negative for it, or if I was ever tested for it via bloodwork.
September 7, 2019 at 8:58 am #49079
There is absolutely no meaning to the small decrease in the IgG result. None. These variations are totally normal.
At least you have some clarification about what’s been going on here.
This is your final post on this subscription. If you have more questions, feel free to renew.
- This reply was modified 4 months, 2 weeks ago by Terri Warren.
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