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How long do I need to wait before I can trust/take the Western Blot?

› Forums › Herpes Questions › How long do I need to wait before I can trust/take the Western Blot?

  • This topic has 2 replies, 2 voices, and was last updated 3 weeks, 6 days ago by Terri Warren.
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    • March 1, 2023 at 3:46 pm #80618
      Jtaranpr
      Participant

      My hsv 2 igg index value was a 1.72. Supplemental igg positive with no index value.

      I am positive for HSV 1, index value of 54. I have had that since I was a kid according to my mother.

      I have no reason to think any of my partners are hsv 2 positive. I have no outbreaks or symptoms nor do 3 of my previous partners.

      Do I need to wait 12 weeks for WB?

    • March 3, 2023 at 12:03 pm #80628
      Jtaranpr
      Participant

      Also I’ve done some reading on your forum and it looks like I’m definitely a candidate for the blot. I’ve already started that process. Question about positive supplementals: you mention that you have over 100 patients with positive supplementals and negative blots. What about patients with low index values and positive supplementals that were POSITIVE on the blot?

      I guess I’m trying to figure out what my odds look like here. With a 1.72 index value for hsv 2, and a 54 for hsv 1. What’s the likelihood of false postive here just from numbers alone? I’ve read that 1.29 is 80ish % false positive which is very high. 1.72 would presumably be somewhere between 57% and 80%.

      Also worth noting, in 2019 I tested for hsv 2 and came back negative. Less than .91.

      What does it mean that 4 years ago I tested negative but now I’m testing positive with a low index value? Does the fact that the number has gone up hold any weight? Or could I go take the test again and possibly be back below .91 again?

    • March 4, 2023 at 1:28 pm #80655
      Terri Warren
      Keymaster

      I think the risk of a false positive for you is around 75%. We simply cannot trust this test at all – not the IgG and not the supplemental. I’ve had index values as high as 17 not confirm as positive by western blot – and this fellow did the test twice, months apart.

      The results will vary greatly – you could do it again and it could be negative, correct.
      Do the blot, you need to be clear about all of this , in my opinion

      Yes, and 12 weeks from any sexual encounter is best

      Terri

      • This reply was modified 3 weeks, 6 days ago by Terri Warren.
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