July 9, 2019 at 10:35 am #41441
Last week I took a blood test at Quest, and these are my results:
HSV 1 IGG, TYPE SPECIFIC AB — 2.03
HSV 2 IGG, TYPE SPECIFIC AB — 1.50
It looks like I’m in the false positive range. That being said, could both figures really be wrong? After skimming other posts, it seems like usually one type is in the gray area, but I haven’t come across any instances where this applies to HSV 1 and 2.
I’m tempted to go to the doctor to get antivirals prescribed, though I’ve never had a cold sore, nor have I had anything atypical happen down south. I have a few questions:
1. What is the ideal time to wait before getting tested again?
2. Would it make the most sense to go to back to Quest?
3. Given that my HSV 1 number is relatively low and so many people have HSV 1, do you think it’s more likely that I’ve had it for many years (vs. a false positive), or would the figure be higher?
July 9, 2019 at 12:14 pm #41455
The timing of any follow up testing has to do with your last sexual intercourse encounter. How long ago was that? If recent, I would recommend AGAINST taking suppression as it can alter the antibody response to the point where results are unreliable.
Was the inhibition assay done as a follow up to your low positive?
Your HSV 1 is lower than most and could be a false positive. I have definitely seen both be false positives when both are low positives.
July 9, 2019 at 4:06 pm #41468
Thank you so much for the speedy reply!
I last had sex at the beginning of May. A condom was worn, and there was no oral sex.
This was actually my first HSV test.
Thanks for the reassurance regarding the potential for a false positive. I’m really hoping that’s the case.
Would you say another IGG test is the way to go? A Western blot seems like the best choice, but it’s a bit expensive for me right now. Also, could the proteins in someone’s blood always cause them to get a low positive on HSV tests, despite being truly negative for the infections?
July 10, 2019 at 8:24 am #41812
You could try another IgG but I’m not clear that it will be much different. The blot is best but I get that it is expensive. You could work on getting it with your own provider so you don’t need to pay a consult fee with me – and your visit with your own provider might be covered by insurance as well.
The proteins could cause both to be false positives, yes
You must register to ask your own question or be logged in to reply to this question.