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HSV 2 equivocal!

› Forums › Herpes Questions › HSV 2 equivocal!

  • This topic has 9 replies, 2 voices, and was last updated 7 years, 6 months ago by Terri Warren.
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    • August 24, 2015 at 7:38 am #8948
      Unknownstatus
      Spectator

      Hi Terri

      Thank you for your time!

      I am a 35 years old heterosexual male. I had protected sex twice with a woman (unknown status) four month ago. I started a new relationship recently, very soon after having unprotected sex with my new girlfriend she had her first GHSV outbreak, that she is aware off

      She had a swap test done, which confirmed a HSV 2 infection. ( no blood test done).
      I started to think that may have been me that could have passed the Virus to her, as an asymptomatic HSV 2 carrier.

      She never tested her blood and never had any GHSV symptoms to her knowledge. Her last sexual encounter was almost 9 month before me. I would also like to point out that she had a full blown out brake. From what I understand that happens most of the time at the first time, very soon as an individual contract the virus (am I wrong?)

      I had and IGG and IGM test done 3 days after her lab result came back positive and approximately 2 weeks after having unprotected sex with her.
      I have never noticed any sores or symptoms in my life.

      My IGM came back negative and my IGG came back positive for HSV 1 but Equivocal for HSV 2. Unfortunately I was not able to get the exact numbers of the test from the lab. They told me to do it again in 2 weeks.

      I am very confused with the seroconversion window of time. Some people say 3 month other say 4, others 6.

      If my IGG came back equivocal after almost 4 month of exposure to my previous partner.

      is it safe to assume that I did not have HSV 2 before this current relationship, and there may still be a chance that I may not have HSV 2 at present moment ?

      Should I still think that in spite all this I may still not be infected with HSV 2 and my high HSV 1 and previous chicken pox is altering the IGG HSV 2 test result making it equivocal ? Or this is most likely a new exposure from my current relationship?

      If I did not have HSV 2 before meeting my new girlfriend. How easy would have been to get infected with HSV 2 if I had unprotected sex 3 days before her Outbreak?

      I would like to know my status, where should I go from here?

      Thank you so much!

    • August 24, 2015 at 8:45 am #8963
      Terri Warren
      Keymaster

      It would be useful for your current partner to get an IgG antibody test. If she has a high HSV 2 index value, this indicates a recurrence rather than a first infection. Then, if you are equivocal, this could mean that you are newly infected and your future IgG will be higher. Or it could be a red herring equivocal and mean nothing.

      If you are indeed not infected (or were not infected before you had sex with her) then if she does have established infection and just didn’t know it, there is some risk of you acquiring HSV 2 from her having sex 3 days before her outbreak.

      The best way to make sense of all this would be for her to have had a swab test accompanied by an IgG antibody test. Then you could have known if this was or was not her first infection.

      I think it is unlikely that you acquired HSV 2 4 months prior and still had an equivocal IgG result.

      Did I miss anything?

      terri

    • August 24, 2015 at 4:15 pm #8969
      Unknownstatus
      Spectator

      Hi Terri

      Thank you for your time!

      I guess I am not really sure if asking my girlfriend for a IGG test at this moment would really be that useful. I am not really interested to know who gave it to whom. What’s done its done.

      I mainly wanted to know if I did not have the virus before, because in that case I may still not have it at the present moment. Right?.

      In spite of my situation, do you think that it’s more likely that I am getting and equivocal result because I just contracted the virus? ( still no symptoms after 3 weeks of unprotected sex).
      How often negative people get equivocal values in their IGG test?

      I would really like to know my status, should I test in 4 weeks for now?

      What if I keep getting equivocal result being in a relation with a hsv 2 positive partner? I am negative or positive?

      I am a little confused about how to go from here

      Thank you so much for your time

      All the best

    • August 26, 2015 at 5:03 pm #8984
      Terri Warren
      Keymaster

      Yes, you may not have the virus, correct. With an equivocal result, it is really not possible to know right now if you are making antibody due to a new infection or its not positive, period.

      Sometimes negative people DO get equivocal results, certainly.

      Figuring this out involves waiting and retesting, no way around that. I do not think your equivocal is due to the previous partner but could be due to the person who tests HSV 2 positive now.

      If you were our patient, we would likely test you in four weeks and see where things stand. If you are still equivocal, then I don’t think you are in the process of developing antibody due to a new infection or it would very likely be significantly higher. If it is still equivocal later, then I would probably recommend a western blot at 16 weeks post last sex with this person.

      Terri

    • August 29, 2015 at 4:10 pm #9054
      Unknownstatus
      Spectator

      Thank you Terri for your time!

      I would defenetly like to take a second test to know my status , (still no symptoms so far). I live in Montana, the only test I can take will be sent to the Mayo Clinic. Unfortunately Mayo clinic gives no number value to the result. They just write positive, negative or equivocal in the results.

      Since there are so many false positives under the 3.5 value, I would like to take a test that gives me a value number. Knowing that this is a life long condition, it would make More sense to take a test that will not let me wondering again whats really going on.

      My partner is HSV 2 positive. We are in a monogamous relation, so if I come to a conclusive HSV 2 positive diagnosis I could let go of all the precautions to remain HSV 2 negative. Until then I should probably consider myself negative and practice safer sex.

      What would you recommend me to do?

      Could you please guide me.

      Should I do the herpes Select? Where could I do that?

      Should I just go strait for the Wester Blot?

      Any other test that may be available to me?

      Is any of this test cover under insurance?

      Thank you so much

    • August 29, 2015 at 4:42 pm #9059
      Terri Warren
      Keymaster

      Hmmmm. There are no Quest labs near you? They give a numeric value. I know Mayo does not – I’ve been round and round with them about this and they are so backwards about the research on low positives – kind of stunning from a place with their reputation. I don’t think you should do the western blot now, too soon, a positive would tell you what you need to know but a negative would not and if money is an issue, I would wait. I have been able to get index values from Mayo in the past but it is NOT easy. I think you might just need to wait and do the western blot at 16 weeks, I don’t see a lot of other options unless you want to travel to another state.

      Terri

      • This reply was modified 7 years, 6 months ago by Terri Warren.
    • August 29, 2015 at 4:47 pm #9060
      Unknownstatus
      Spectator

      Hi Terri

      Thank you so much for your fast response …
      I found a quest lab in Butte Montana (2 hours drive from me)

      This is the info online:

      Quest Diagnostics – Butte PSC
      401 S Alabama St Butte MT 59701-2315

      Is this the place I should go to?
      what kind of test will they do?

      Thank you again

    • August 31, 2015 at 2:28 am #9066
      Terri Warren
      Keymaster

      Yes, this is the place you should go. You want an HSV IgG type specific antibody test. Do you think your doctor could order this for you? Someone has to order this – you can’t just show up there for the test without some kind of order

      Terri

    • September 21, 2015 at 12:15 pm #9588
      Unknownstatus
      Spectator

      Hi Terry

      Here again trying to solve my HSV mystery. I just got my result of my second test after Geting and Equivocal result, ( just to remind you, I am in a reletionship with a woman that tested positive for HSV 2, 2 month ago).

      My blood was sent to the CDD, they did and Elisa test. It came back negative for HSV 2.

      Should I take this negative after equivocal as a definite negative?

      How likely are false negative results?

      Regarding discordant coples. My girlfriend takes antiviral medication and we use condoms all the time. Should I trust the statistics that claim that the chances of contracting HSV 2 are 1% a year for a negative male and positive female?

      Feeling very relive!

      Thanks for everything!

    • September 21, 2015 at 10:36 pm #9611
      Terri Warren
      Keymaster

      Yes, you should trust the test results, but remember that these results are always a moving target when you are having sex with some one who is HSV 2 positive. The reflect infection status about 3 months ago and backward. And yes, your statistic is correct.

      Terri

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