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Hsv-2 IgG 4.2, Supplement positive. False or Double test?

› Forums › Herpes Questions › Hsv-2 IgG 4.2, Supplement positive. False or Double test?

  • This topic has 1 reply, 2 voices, and was last updated 2 weeks, 2 days ago by Terri Warren.
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    • February 27, 2023 at 6:46 pm #80584
      OperatingSpeculation
      Participant

      Hi Terri,

      Thank you for starting this site. I recently did a panel for STD and came back negative on all but HSV-2. My IgG tested at 4.2 and a positive supplement test followed. My labs went through Labcorp and I’ve been seeing you mention Labcorp can show false positive but that a negative supplement is closely related to a negative Warren Blot Test. Mine came back positive. I’ve only had sex with one person this year and they came back clean. I’ve never had a break out either.

      I’ve read they do the supplement test by weighing the antibodies but can be confused with other antibodies.

      Should I go ahead and check with the Warren Blot test or was the supplement testing results a good test?

    • March 4, 2023 at 12:12 pm #80636
      Terri Warren
      Keymaster

      The supplemental test can certainly be a false positive – I now have 112 patients with this situation.
      The western blot “weighs” the antibodies, sort of
      If you want to be really certain about your status, I do recommend the western blot yes. it is considered the gold standard of herpes antibody testing.

      Terri

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