June 29, 2019 at 7:58 am #39730
Hi Terri I hope all is well.
Facts and Circumstances
In February of 2018 I did my annual full panel test which included HSV I and HSV II through Quest. I tested positive for HSV I with an index value of 40 and less than .90 for HSV II (IGG test)
June 21 2019 I did another full panel test but this time I asked to to exclude HSV I since I know I have that (cold sores as a child) however my HSV II came back at 1.64 this was also an IGG test but was done through Sunrise labs.
I had a protected sexual intercourse with a woman on June 6 2019, who I deem low risk. Unfortunately the condom did break during intercourse and it may have been a few minutes before I realized. I’ve known her for years and I know she gets tested just not sure for HSV. I don’t want to ask her just yet to avoid setting off any unnecessary alarms.
I have never had any symptoms.
How likely is it that this test is false positive given that I have such high hsv I antibodies, and how long do antibodies take to develop after exposure such that the index value provides a definitive result(i.e more than 3.5)?
It is possible for different labs to use different brands of tests (i.e herpselect vs diasorin) which would yield different results? I’ve always used Quest and the first time I use Sunrise my results have come back positive. I tried calling them to find out the manufacturer of the test but they did not know.
July 4, 2019 at 3:12 pm #40742
You are testing in the low positive range and need a confirmatory test to sort this out. And yes, different labs may use different brands of IgG tests and results may not be consistent across different brands. I would suggest the western blot for the confirmatory test. Another option would be to go back to Quest and see what you get on their test.
In terms of timing, it is wise to wait 12 weeks for a final test after a concerning encounter like a broken condom.
September 4, 2019 at 7:08 pm #48928
I went back and got tested again this time through Quest. Results came back positive with an index value of 1.69.
I still have never had any symptoms.
By now, if I was absolutely hsv II positive wouldn’t the results come back at least 3.5? What are the chances this is false positive?
What are you thoughts on doing a confirmatory test via quest and also a western blot? I mention both because I do not think I can wait longer. Thanks.
September 7, 2019 at 9:37 am #49091
No. Some people who are truly positive and infected just have low positive results. At 1.69, there is probably a 75% chance that this is a false positive.
I am not a fan of the confirmatory test from Quest as I have seen a significant number of cases where the confirmatory test from Quest and the western blot don’t agree and clearly, the blot is the gold standard. If you were my patient, I would suggest that you wait 12 weeks from any concerning encounter and do the blot.
September 17, 2019 at 1:05 pm #49675
Hi Terri I’d like to the blot. Does your service include phone consultations? I can’t do video since I’ll be at work. I reserved a slot and sent a note asking if a phone call would work, but I haven’t heard back yet. Thanks.
September 21, 2019 at 6:59 pm #54046
If you reserve a spot for a video conference AND show up in the waiting room for even a minute, we can do it. You can tell me immediately that you can’t do a video conference and I’ll call you on the phone. I need you to show up for a moment so I can do charting and billing. Will that work for you?
This is your final post on this subscription. If you have more questions, we can address them on the phone.
- This reply was modified 4 months ago by Terri Warren.
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