Hi Terri I hope all is well.
Facts and Circumstances
In February of 2018 I did my annual full panel test which included HSV I and HSV II through Quest. I tested positive for HSV I with an index value of 40 and less than .90 for HSV II (IGG test)
June 21 2019 I did another full panel test but this time I asked to to exclude HSV I since I know I have that (cold sores as a child) however my HSV II came back at 1.64 this was also an IGG test but was done through Sunrise labs.
I had a protected sexual intercourse with a woman on June 6 2019, who I deem low risk. Unfortunately the condom did break during intercourse and it may have been a few minutes before I realized. I’ve known her for years and I know she gets tested just not sure for HSV. I don’t want to ask her just yet to avoid setting off any unnecessary alarms.
I have never had any symptoms.
How likely is it that this test is false positive given that I have such high hsv I antibodies, and how long do antibodies take to develop after exposure such that the index value provides a definitive result(i.e more than 3.5)?
It is possible for different labs to use different brands of tests (i.e herpselect vs diasorin) which would yield different results? I’ve always used Quest and the first time I use Sunrise my results have come back positive. I tried calling them to find out the manufacturer of the test but they did not know.
You are testing in the low positive range and need a confirmatory test to sort this out. And yes, different labs may use different brands of IgG tests and results may not be consistent across different brands. I would suggest the western blot for the confirmatory test. Another option would be to go back to Quest and see what you get on their test.
In terms of timing, it is wise to wait 12 weeks for a final test after a concerning encounter like a broken condom.
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