HSV2 false positive?

[Aquafina22]

22year old female

I had a boil like single pimple on my vagina (pubic area) which has been around for months, I want to say since October or November. I took a needle and popped it which I know wasn’t a good idea and blood and puss came out. This pimple didn’t hurt or itch or anything. After popping it the pimple remained and only keep filling up with puss and blood so I just left it alone. (I didn’t know much about hsv2 so I didn’t think to get it swapped)

I had STD testing done with my doctor (April 5th,2022) which included HIV, chlamydia, and gonorrhea which all came back negative

My sexual encounters were:
December 2nd, 2021 protected
December 23rd, 2021 protected
January 23rd, 2022 protected
February 8th, 2022 unprotected

I decided to get hsv1 and hsv2 testing done at “Any lab test now” to see if this pimple could possibly be related to herpes. On May 5th, 2022 my results came back as

HSV1 > 5.00
HSV2 1.17

I’ve never had a cold sore before and I’ve never had an OB (not sure if the pimple would be considered an OB). I went on wisp and ordered acyclovir, took it for a week which didn’t clear up the pimple at all so I decided to switch to Valtrex 1000mg outbreak dose for 5 days. The pimple is completely gone now and after the outbreak dose I started Valtrex supression which is 500mg daily. I’ve been taking this for 9 days now. After doing more research my mind started to wonder and I read a lot about false positives so I decided to go back in and get retested.

On June 1st, 2022 my results came back as

HSV1 > 5.00
HSV2 1.01

My question is
1.) do you believe that the antivirals could have caused a change in my results and could this be hsv1 be genitally ?

Also would you advise me to go off antivirals and take the western blot?

Thank you!

[Terri Warren]

If you’ve never had a cold sore in the past, it isn’t possible to know if your HSV 1 infection is oral or genital but your symptoms of the bump sound nothing like herpes. And no, I don’t believe the antiviral made the change. your positive was just barely positive the first time so the difference is very minor indeed. If you would prefer greater certainty, you could do the blot but I suspect it will be negative based on what you’ve said so far.

Terri

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