February 9, 2015 at 2:29 am #3645AnonymousInactive
I wished I had come across your site sooner. Thank you for having this informative site.
Like many posters before me have asked about high hsv1 possibly causing a false positive hsv2, I am curious about my situation.
In Feb 2013 I was neg for hsv 1 and 2. In mid Dec 2014 I got tested for all STDs and a few weeks later was notified that I tested positive for both: hsv1 = 6.09; hsv2 = 2.64. I was shocked and in disbelief, so I went to a different OBGYN 10 days later and they tested me for hsv2 only with a result of 2.68. So my question for this is, am I definitely positive for hsv2 since the second time I wasn’t tested for hsv1? Or does this not matter and hsv1 could still possibly be causing the false positive hsv2? Both labs were lab corp to my knowledge b/c that’s what my health insurance supports.
I have had 2 partners in 9 years. I let me new partner (of about 5 months) know that i had tested positive. We’d had sex about 5 times, 3 times unprotected- the first unprotected time was Sept. He just received his results and his are negative–I’ve seen his results with my own eyes. My previous partner was a long term, on again off again relationship, so we’d had multiple unprotected sexual encounters. So with my recent partner being negative, it has to be my ex (if in fact I am infected with hsv2). I’d never noticed any symptoms on him and he has never mentioned anything to me about seeing symptoms. I am so in denial and depressed, etc, etc. My next question is would you honestly suggest that I get a western blot? With all of the posts about false positives for results under 3.5, I’m curious if I would benefit from western blot. If you do suggest western blot, how exactly do I do it? I saw you post on another thread: “The second way would be to contact our clinic, become a phone patient of ours, and we can order the blood drawn at a Quest laboratory near where you live.” Is this still true? I am on the east coast. How long does the western blot test take?
How many times have you seen a situation like mine (positive hsv 2 result around 2.6) and their western blot come back negative?
Thank you for your time. I appreciate it.
February 9, 2015 at 3:59 pm #3648
You definitely need a western blot. At your index value level, there is about a 40% chance that you value is a false positive. I think this is especially true since you were negative for both in 2013 and now are positive for both and also since one of your two partners has tested negative for HSV 2.
What state do you live in?
February 9, 2015 at 4:20 pm #3653AnonymousInactive
I live in MD.
Did it matter that I didn’t have hsv1 tested again but the hsv2 still came back positive? Was there some sort of cross contamination, etc? I am trying to understand the science behind the hsv1 giving false positive hsv2 results.
I had also asked how many times have you seen a situation similar to mine and the blot cam back negative.
Thanks a lot Terri.
February 10, 2015 at 4:09 pm #3674
I often see people with this kind of situation be negative by western blot for HSV 2. As I said aboe, I would guess there is about a 40% chance that your HSV 2 is a false positive. That means that out of 100 times when I see someone who has an HSV 1 positive that is high and an HSV 2 that is in the range, 60 people confirm their HSV 2 index value as a true positive and 40 people turn out to be negative for HSV 2 by western bot.
It doesn’t matter at all that you only tested for HSV 2. There likely is some cross reactivity between the two antibody tests.
February 10, 2015 at 4:36 pm #3676AnonymousInactive
Thank you. I will call your office today to see about ordering the western blot. I’d like to get this done ASAP….My sanity depends on it.
February 11, 2015 at 3:37 pm #3692
You must register to ask your own question or be logged in to reply to this question.