Please Help-Confused on Equivocal Results

[AllincinciParticipant]

Hello, Will appreciate your insight to my situation. On 9/23/18 I had protected sex with a unknown at the time HSV2 and 1 carrier.

I have had no symptoms and the the following tests were all IGG:

Tested on 10/1/18 and was negative.
Tested again on 10/15/18 (3 weeks from encounter) and result was 1.00.
Retested on 10/29/18 (5 weeks post encounter) and result was .94.
Tested again on 11/12/18 (8 weeks post encounter) and result was negative. Tested again on 1/29/19 (18 weeks post encounter) and result was 1.01.

What’s the probability I am infected?
Should I continue to be tested or have a western blot test?
Is there anything else that could cause my IGG to be equivocal on a regular basis?

Thank you for your help……

[Terri WarrenKeymaster]

You don’t mention if this is your result for hSV 1 or HSV 2?
If for HSV 2, I doubt that you are infected but I recently had a patient who had a 1.03 on her IgG and confirmed as positive by western blot so I’m less certain these days about equivocals being negative. you may have a protein in your blood that has a similar molecular weight to HSV 2 and that is tripping the IgG in error. The western blot will clarify your situation. This is more likely to be a negative if the result is for an HSV 2 antibody test than HSV 1.

Terri

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