March 8, 2019 at 6:29 pm #31569
Hi Terri – thanks for the forum.
I (male) had protected sex (condom) with a new partner (female) on February 1 of this year. Within a week of that encounter I was having some unusual symptoms, including a “burning” feeling in my groin and above my anus (though I could not see any rash or redness in these areas). I have also had discomfort in my groin and under my armpits that I interpreted to be swollen lymph nodes. The groin discomfort resolved within about a week but the discomfort in my armpits has persisted for the last month.
Around 2/14 I noticed two bumps on my scrotum near the base of my shaft. They appeared red and were painful at times but did not seem to sit on the surface of the skin or be filled with fluid. They never turned into ulcers or scabbed. The remnants of these bumps are still around today though seem to have healed a bit.
Around 2/21 I noticed a blister-like sore right below my waistline that was mildly painful. This new sore led me to schedule an appointment at an urgent care clinic.
My appointment was on 3/3 and the Physician visually referred to the sore near my waistline as a “lesion.” He took a swab test and a blood test and prescribed me 10 days of Valtrex.
I got the lab results yesterday:
Herpes Culture (VCM) – HSV not detected
HSV 1 IGG = <0.90 (index)
HSV 2 IGG = <0.90 (index)
Quest was the lab that ran the tests.
I now realize there are a few imperfections with these tests:
1) The viral culture is pretty useless given how old the sores were at the time. I actually thought he was going to run PCR and only realized he did culture when I got the results
2) I was only about a bit over 4 weeks after potential exposure for the IGG tests
My question: Based on this information how likely do I have Herpes at this point? I understand I need to be retested in another 2 months for a more definitive IGG result. I’ve never had symptoms like I described which makes me wary of accepting these results.
March 13, 2019 at 4:57 am #31714
One other question: How long do the lesions typically last? From the anecdotal information I have read they seem to progress and change quickly for many people (appearing and resolving over the course of a week).
Is it unusual for a lesion to last 3-4 weeks, even if it is the first OB?
March 16, 2019 at 7:40 pm #31965
It seems my questions were overlooked but I found my answers.
For anyone else that is curious about the time to seroconvert and show a positive result after the onset of symptoms from a primary result, you can view the study below:
Quest uses HerpeSelect IgG ELISA for testing.
Per Quest: The median interval between symptom onset and IgG seroconversion (for HSV-2) was 21 days for the HerpeSelect ELISA.
Reading the linked study and associated figures, the time it takes to see a positive HSV-2 IgG test result after onset of symptoms for a primary outbreak:
50% seroconvert by 21 days
77% by ~42 days (6 weeks)
93% by ~90 days (3 months)
At the time of my test I was just over 21 days after potential symptom onset so the test results aren’t very meaningful. However, it did rule out prior infection and isolated the partner so it was useful for that purpose.
Anecdotally, it seems most classic lesions resolve relatively quickly (around 1-2 weeks) but I found some (subsequently confirmed) examples of the lesions lasting longer before healing.
March 19, 2019 at 10:51 am #32370
These statistics are correct. You are early to test but do have a baseline result.
The other part that the company does not report nor is it in this particular study is that the IgG test misses 30% of HSV 1 and 8% of HSV 2 (paper published in 2017).
Some people’s outbreaks can last up to three weeks with new infection.
You must register to ask your own question or be logged in to reply to this question.