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Hi Terry,
its been a long wait and still long way to go for the 12-13-14 weeks period. In the meantime i been getting tested
THe test from Quest always come back as negative HSV 2 .89 not an actual value index, managed to talk on the phone with people from quest and they said that they do not put a actual index value, they always put negative, equivocal or positive. On the other hand the test “HSV 2 Glycoprotein G Ab, IgG” by Solstas came back with a .17
The last test that i took was at 6 weeks after exposure and it came back negative. do you know why or how to interpratate the absence of an index value.
Regarding symphtons, guess i could say mine were atypical if at all herpetic related. Right know Im only experiencing fatigue, mild pain in both legs, and lower back and strep throat that has not gone away after 6 days on antibiotics. are these herpes related? I see that many people get these as a sign of an outbreak, if this is my case i don’t develop actual blisters or sores, and these alerts have been going on for couple of weeks now or so.
Could you explain about seroconversion or guide me to more info on that. just a s a reminder i took acyclovir for 20 days (you told me in a different question that)a 13-14 week wait time would be enough for another serum test).
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Some labs just don’t report out index values, especially for negatives. Some do. I don’t think it has any meaning. Your negative is really low.
None of your symptoms, without a lesion, makes me believe that you have herpes. And then you have the negative test to help reassure you for now. I still believe, given three weeks of medication, that you should wait a few more weeks than normal for a reliable test. I’m not sure what you mean about seroconversion – that just means going from negative to positive on an antibody test.Terri
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We don’t know why the test misses a few people out of 100 with the screening test. But we know they almost always make antibody because western blot picks it up. It is likely that they may not make one particular protein that the screening test looks for or may not make it in adequate numbers to be detected but they do make the other proteins that are detectable by western blot.
Yes, I have lots and lots of patients who believe they have herpes and can’t let go of the worry and are not infected.
Terri
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1. I wonder if these are truly signs for a persistent 1 month outbreak or could be just I don’t develop lesions. Could I have it and just not showing up in my blood?
I seriously doubt that that is the case! Herpes just doesn’t normally behave at all in this way.
2.As I understand during the outbreak, your body is already fighting the infection, if this is the case it should show up in my blood right?
It can take up to 12 weeks to show up in the blood as the immune system continues to fight the virus.
3. My testosterone is low (clinically tested, levels low) probably cause all the stress and depression that I’m going through right now. Could these actually affect my blood work or alter my immune system, therefore not creating antibodies?
No
4. On an optimistic scenario, 8 weeks after exposure what are the chances of staying negative?
Over 70%
Terri
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I can say that you are still soundly negative and, if the value stays low like this, with 98% certainty, compared to herpes western blot the gold standard you do NOT have HSV 2. Period.
Terri
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I don’t think that three weeks of antiviral therapy requires months more time to allow for seroconversion – perhaps a western blot at 18 weeks would give you the answers you seek? Or 14 weeks with the ELISA screening test.
Terri
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