May 13, 2020 at 3:07 am #70159
I hope you and you’re family are staying safe during these trying times. Also, thank you for everything you do….moving on.
So back in September 2019 I took a WB test with negative results on both HSV 1 & 2. It had been over 10 months without any sexual contact whatsoever. But in June of 2019 I had a single lesion, what looked like a very very small sore (1mm or less) on my scrotum. Then another one in September, same size around the same area. I never went to get a PCR done because of my work schedule during the week was always so long, 12-16 hour days. So by the time I was off majority of places would be closed. Now fast forward to Saturday May 9th I notice another very very small single lesion on my penile shaft this time. It’s probably 1mm in size and red. I understand it’s probably too late now to have this swabbed but, should I get this swabbed if it happens again?
A part of me thinks the skin is irritated or broken because I have a genital wart near this area, i.e. right next to it and have been using Aldara to treat it, which a couple of days I forgot to wash off the aldara. Could this be a break in the skin from Aldara?
Because I noticed no elevated bump here or blister here, just woke up with a small red circle that has what looks like a scab over it.
I’m really frustrated because I thought all this anxiety and worry about not knowing whether I had it or not was put behind me in September of 2019. Now it seems like this has opened up a whole new can of worms.
What is your opinion on all this?
Could this be GHSV 1 and the blot didn’t detect it?
What are the odds of that happening?
May 15, 2020 at 10:01 am #70229Terri WarrenKeymaster
Aldara is most definitely going to have that side effect if you forget to wash it off. One of the functions of Aldara is to create irritation of the skin so that immune cells will come to the area and begin to recognize the HPV. Otherwise, HPV just sits on the surface of the skin and there is no interaction between the immune cells that are around and the wart. Does that make sense? When I was seeing patients and using Aldara, this was the most common side effect that I saw.
May 15, 2020 at 12:19 pm #70246
Yeah that definitely makes sense. So as it stands now, you believe the sore to be from the Aldara rather than HSV, which I keep testing negative for through the blot and through the IgG? Because this sore has been here now for 7 going on 8 days. Obviously if it happens without using Aldara then go get it swabbed, but for now I can probably assume it’s from my own negligence?
May 17, 2020 at 12:16 am #70266
Because the HPV bump, is about 5mm away from this lesion which is a small red circle with a scab over it roughly 2mm in size. Basically it was where healthy skin was but I know for a fact Aldara was put on this patch on skin and left on for multiple days in a row continuously. It has been present going on 10 days now. It seems to be slowly healing but it has me a little paranoid. That’s why I’m curious about the PCR, maybe being a more reliable option?
But what you’re saying is you’ve seen sores and/or tiny ulcers form from the overuse of Aldara on healthy skin cells due to the irritation it causes?
Apologies for the redundancy in questioning but I need your opinion, because ultimately I want to know for sure if i have this or not. I’ve been tested so many times (IgG 10 or more/ Blot 1 time; all negative).
I’ve read in the forum that you’ve had 10 patients in 35 years test negative on the blot but swab positive on a PCR. My question for you now is this…
Out of those 10 were more infected with HSV 1 or HSV 2 when swabbed?
Has there been a study done on the percentage of people that are believed to not serocovert?
May 21, 2020 at 6:53 pm #70296Terri WarrenKeymaster
I have totally seen Aldara that spread to healthy skin cause skin erosion and subsequent scabbing, yes.
For the record, most people who test negative but have symptoms that concern them, think that they are #11 of the people who have herpes but test negative on the blot. I do not agree that that is the case. Remember that ALL of these 10 people tested positive on a swab test for herpes. That isn’t you. There have been lots of research done on the blot that suggests that it is 99.9% sensitive for HSV 2 and 95-96% sensitive for HSV 1. You have a very logical explanation for the skin breakdown that you have noted. I would encourage you to accept that. If you get another lesion unrelated to the application of Aldara, have that swab tested right away.
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- This reply was modified 6 days, 11 hours ago by Terri Warren.
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