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Should I get a western blot?

› Forums › Herpes Questions › Should I get a western blot?

  • This topic has 2 replies, 2 voices, and was last updated 3 weeks, 3 days ago by Terri Warren.
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    • February 16, 2023 at 9:31 am #80466
      extraaccount
      Participant

      Hello, I have been in a monogamous relationship since 2018 with someone who is positive for HSV-2. He knows his pre-breakout symptoms really well and we never had sex around outbreaks. He started taking daily/suppressive Valtrex in 2019 and thankfully it works really well for him and he has never had an outbreak again since starting Valtrex. So, his last outbreak was 2019 before Valtrex and my last STD panel was in February 2020. I was negative for everything on this panel in Feb 2020 except HSV-1, which I already knew I had (my value for HSV-1 on that test is 23.5).

      I just got my 10-panel STD results back yesterday and it came back positive for HSV-2. My “HSV 2 IgG, Type Spec” test result value is 1.27 and the “HSV-2 IgG Supplemental Test” came back positive as well. I have never experienced any symptoms of HSV-2. This testing was done through LabCorp, and I am unsure if it is important or not to mention, but I did have a high dose of biotin within 24hrs and I read the HerpeSelect test results can be skewed by biotin (I am unsure if LabCorp does HerpeSelect test or a different one).

      Should I accept I have HSV-2, or do you think there is a good chance it is a false positive and pursuing a re-test or Western Blot test is worth it? I don’t want to get my hopes up and am feeling a little stupid and defeated. Thank you for your any help.

    • February 16, 2023 at 12:09 pm #80468
      extraaccount
      Participant

      ETA – I am sorry I forgot to mention the testing company I use is recommending a “HSV-2 IgG Inhibition, IA” for further confirmation. I doubt it is as reliable as the western blot, but easier to do, so I am not sure if I should consider it or not. Thanks again!

    • February 23, 2023 at 1:47 pm #80516
      Terri Warren
      Keymaster

      Do NOT accept the LabCorp results and DO NOT do the inhibition assay as there have been false positives on both of these. Do the blot if you can afford it. If you tell me where you live, I can tell you where you can get your blood drawn locally but you cannot order this yourself. you need a clinician to order it for you.

      Terri

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