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Should I get Western Blot? Help Understanding Results

› Forums › Herpes Questions › Should I get Western Blot? Help Understanding Results

  • This topic has 3 replies, 2 voices, and was last updated 1 month ago by Terri Warren.
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    • February 19, 2023 at 7:15 am #80481
      smith28
      Participant

      A month ago I tested for HSV1&2 and others at the request of my partner so we could have unprotected sex. I came back positive for both and was very surprised and distraught b/c I have never had symptoms. My last sexual partner prior to this was in October.

      1st Test
      HSV 1 > 58
      HSV 1 2.42

      IGM Negative for HSV1 & HSv2

      2nd Test (went somewhere else to get tested because I thought retesting was how you confirmed)

      HSV1 > 58
      HSV2 2.10
      No supplements

      3rd Test (asked for my results to be emailed and saw that confirmation testhad to be a inhibition assay not just going to get tested again.

      HSV1 > 58
      HSV2 2.20

      Inhibition Assay

      The HSV-2 gig screening assay was repeated on a different platform as part of the inhibition testt and the result was negative.This the inhibition result could not be determined. Most samples exhibiting this type of discrepancy have initial HSV-2 IGg index values of 1.10-3.00. If early HSV02 infection is suspected submission of another sample collected 2-3 weeks after is recommended.

      A positive inhibition interrpretion indicts true hsv-2 specific reactivity, whereas a negative suggests that the positive screening index is falsely positive.

      Does this mean I am negative? Should I get a western blot? I doubt timing is the issue and my current partner does not have it. Please advise.

    • February 24, 2023 at 3:41 pm #80536
      Terri Warren
      Keymaster

      I believe that you are very likely negative for HSV 2. WE see false positive inhibition assays, but when the IA is negative, that’s a very good sign. We could do the blot, for sure, if you need more reassurance. Let me know

      Terri

    • February 26, 2023 at 9:20 am #80576
      smith28
      Participant

      okay thank you, can you also change my username from my email? I submitted two forms about this and haven’t heard anything back. Thanks again

    • February 28, 2023 at 7:30 am #80599
      Terri Warren
      Keymaster

      I changed your username as you can see.

      Terri

      • This reply was modified 1 month ago by Terri Warren.
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