April 1, 2021 at 10:52 am #73174anon9753Participant
First off thank you for all your helpful research and insight, it is very informative
My (Male – heterosexual – 32) situation dates back to 2015. I have never experienced any visual or physical symptoms. All information and test results concern HSV2 (all HSV1 results have been negative). All samples were taken at Quest Diagnostics.
On December 5, 2016, I received an equivocal HSV2 Igg result of 0.96. My PCP mentioned I may have been exposed and to be tested again in two months for confirmation. Again no symptoms, nor did any any partner disclose any HSV information.
On February 8, 2017 I received a negative HSV2 Igg result of <0.90. I felt very relieved and didn’t think about it until I began a long-term relationship (July 2017) and decided to get tested again.
On May 3, 2019, I received a positive HSV2 Igg result of 1.26. I again felt very concerned. I did a ton of research and saw your information that positive results between 1.10 and 3.50 without symptoms have a high chance of being false positives. It took me a while to complete (since I’m not in WA State), but decided to get a Western Blot test.
On May 5, 2020, I received the negative HSV2 Western Blot result. I felt ecstatic, considering this had been in the back of mind since the first equivocal result. I did end the long term relationship, and may start a new one soon so I decided to get tested again. I was sexually active between when the relationship ended and the test below.
On March 22, 2021, I received a positive HSV2 Igg result of 1.23. One note is that I did receive my first dose of the Pfizer COVID-19 vaccine on March 17, 2021.
These positive values are low that I wish to believe they are false-positives, yet it is still very concerning thinking that i could be asymptomatic and pass HSV2 along without my knowledge. Should I request and submit another Western Blot test for additional confirmation? My main question now is how I should proceed, or at least your recommendation. Thank you!
April 4, 2021 at 6:39 pm #73181Terri WarrenKeymaster
For people who have low positive IgG results for HSV 2, I find that they will always have them, or at least an equivocal result. YOu did the western blot to clarify your position. I think you should continue to believe that and stop doing IgG tests as a screening mechanism. If you do the western blot again and it is negative again, I think you should believe that you will always be reactive on the IgG. And if you decide to the IgG again, you should be looking for a value that is significantly higher, like 3.5
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