I’m a 26 year old male who had a one night stand, unprotected sex oral and vaginal with someone who’s status I don’t know. Three days later I experienced extreme fatigue, sore throat and swollen lymph nodes in my neck and the left side of my groin. Approximately 3 weeks later I had a burning sensation in my scrotum and the head of my penis. I also experienced body aches and pains isolated to the left side of my body. This persisted for 3 weeks.
4 weeks after the potential exposure I took a full panel STD Test. Everything came back negative except I was Igg positive for HSV1. I’ve had cold sores on mouth as long as I can remember so this did not surprise me. 13 weeks after the potential exposure I again tested negative for HSV2 Igg.
I’m confused because I was expecting to test positive because I’ve never experienced symptoms like this before in my life.
4 days after the potential exposure I started taking valacyclovir. 1 gram tablets twice a day. I continued with that dosage for about a month. I then dropped the dosage down to 1 gram once a day for the next two months leading up to my 13 week test.
Could taking the valacyclovir and having an existing HSV1 infection have caused me to receive a false negative on the HSV2 Igg test at 13 weeks?
If so what steps should I take to receive an accurate and conclusive test result?
Is it at all possible to be reinfected with HSV1?
Yes, taking antiviral medicine to treat a genital herpes infection that you don’t even know that you have can definitely impact antibody test results and cause a false negative. I would recommend that someone wanting an accurate IgG test after a possible new infection refrain from antiviral therapy for three months prior to taking another IgG test. Once you have HSV one at one location under your body, it would be extremely unlikely to get it in a new location
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