VZV vaccine protection against HSV1/HSV2?

[curiousresearcher]

Hi Terri!

Thank you very much for sharing your knowledge and providing continuous support to those seeking help.

I just wanted to get your opinion on the following subject, couldn’t find any previous questions related to that.

There was a study done in Paris by Jacqueline Le Goaster et al. and published in 2012, searchable by “efficacy of anti-vzv vaccine in HSV1 and HSV2”, which claims, according to my understanding, that VZV vaccine may have an effect on suppressing recurrent HSV1/HSV2 outbreaks. Seems like the study was made on subjects already experiencing recurrent outbreaks. However, there is no mention of preventing an initial infection or even possibly initial infection entering latent stage.

Do you think that proper VZV (HSV3) vaccination may potentially prevent HSV1/HSV2 initial infection? Could it be related to the amount of viral load introduced into the system and may be just helping to fight the virus entering the system more effectively before it reaches the latent stage, thought a cell-mediated immune response/killer cells may be?

Would you recommend VZV vaccination as a method of reduction of recurrent HSV1/HSV2 outbreaks?
Would you recommend VZV vaccination as a method of protection from an initial HSV1/HSV2 infection?

Thank you.

[Terri Warren]

I haven’t been able to find that article in PubMed. However, in general, herpes experts agree that neither the VZV vaccine given to children nor the shingles vaccine given to older adults have efficacy for either prophylaxis or prevention of HSV.

Terri

[Concerned & Curious]

Apologies for commenting on another person’s thread, but I have read this, too, and was similarly curious.

Here’s the link to a summary of the study:

https://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3-vaccine-in-hsv1-and-hsv2-recurrent–peer-reviewed-article-OAJCT

Conversely, I don’t suppose HSV-2 affords any immunity, whether whole or in part, to any of the other herpes group viruses, besides HSV-1.

[Terri Warren]

I have contacted my other herpes colleagues and we all feel this is neither a credible journal (not available on PubMed thus not peer reviewed) and not a well done study. HSV 2 does not confer any immunity from other herpes viruses, no. One of my colleagues had had a few patients try this only to have recurrences abate for a while and then return.

Terri

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