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Over 4 years ago I tested positive with a standard test with a score of 1.5. I never had an initial outbreak or visual symptom, but I know that not all symptoms are visual. Earlier this year I took a western blot test that came back indeterminate. 3 months later I took a 2nd western test that was improperly ordered that did not do the seroconversion panel (paired sera). This test also came back indeterminate. Because both of these tests came back indeterminate I was told by the lab to wait 3 more months, then send a new sample to do the paired sera analysis with my very first sample. This would put my first and third test samples 6 months apart.
Because I originally tested positive years ago and there’s no chance I have been exposed to hsv2 in the past 12 months, I am thinking the paired sera test could come back indeterminate. If this were to happen what would that mean?
To my understanding if the paired test comes back indeterminate that would mean I have some levels of antibodies, but would this result mean I am asymptomatic but contagious? Would it mean there is something else I have been exposed to that created similar proteins in my system?
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That is not how to interpret two indeterminate, done 6 months apart. It is extremely unlikely that you have HSV 2 and very likely that you have something else in your body with a similar protein that is tripping the HSV test. We see this often. If I were you, I would consider myself negative.
Terri
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Yes, it is incorrect to assume that 2 western blot indeterminate results 6 months apart from each other means I am asymptomatic and contagious. If I had two indeterminate 6 months apart I would assume I was not infected.
Terri
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