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1) When estimating HSV2 seroconversion rates and testing, were the studies making an estimate from the last exposure or from the time when symptoms developed and were reported?
From the exposure
2) Is it possible to be completely asymptomatic during the first three weeks of an infection and still shed virus? Or is it just that most people aren’t aware of what to look for?
It is possible, yes, to shed virus when you don’t realize you infected. But also most people don’t know what to look for.
2) I guess I am a bit confused about this point: Is the amount of viral shedding during the initial months different in cases of asymptomatic vs symptomatic infections?
It is more common in symptomatic infections.
3) I’ve heard people say that HSV1 negative individuals are more likely to be symptomatic during their initial HSV2 infection. Is there any truth to this? If there is, what is the likelihood that someone with this profile would have symptoms relative to someone with a longstanding hsv1 infection?
there is absolutely truth to that! A person with long standing HSV 1 infection is less likely to notice symptoms of HSV 2 new infection.
4)I’ve read on your website that during periods of shedding you recommend people sleeping with thicker clotthing to prevent incidental genital contact (I think). How long does HSV2 reside outside the body?
I believe what I said was that during an OUTBREAK it might be good to wear underwear to bed, because sometimes sexual contact is so instinctive, that the brain is not in gear yet because of sleep but the penis is wide awake.
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