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Reply To: "Low" igg hsv2, High hsv2; Western blot testing?

› Forums › Herpes Questions › "Low" igg hsv2, High hsv2; Western blot testing? › Reply To: "Low" igg hsv2, High hsv2; Western blot testing?

February 10, 2015 at 4:09 pm #3674
Terri Warren
Keymaster

I often see people with this kind of situation be negative by western blot for HSV 2. As I said aboe, I would guess there is about a 40% chance that your HSV 2 is a false positive. That means that out of 100 times when I see someone who has an HSV 1 positive that is high and an HSV 2 that is in the range, 60 people confirm their HSV 2 index value as a true positive and 40 people turn out to be negative for HSV 2 by western bot.

It doesn’t matter at all that you only tested for HSV 2. There likely is some cross reactivity between the two antibody tests.

Terri

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