There is no good evidence that in the BODY Lysine does anything to help with herpes – this is different than in a petri dish where most of the urban legend about lysine -arginine comes from. the metanalysis study of lysine did not show a benefit from taking this amino acid as it relates to herpes. One must be cautious because many of the lysine studies are poorly done.
But to answer your question, antiviral don’t make a difference in testing either UNLESS they are taken for an extended period of time immediately after a brand new diagnosis. And Lysine has no impact at all.