Reply To: Herpes Questions › Forums › Herpes Questions › Herpes Questions › Reply To: Herpes Questions December 5, 2022 at 12:32 pm #79595 Terri WarrenKeymaster WE have no data on the rate of PCR false negatives as there is no better test to compare it to. I think 12 weeks off medication should be adequate for seroconversion but if you wish to wait 16 weeks, do it. Terri