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Reply To: HSV-2 IGG (varying levels)

› Forums › Herpes Questions › HSV-2 IGG (varying levels) › Reply To: HSV-2 IGG (varying levels)

March 13, 2023 at 8:01 am #80724
Terri Warren
Keymaster

If I have been HSV2 positive for 8 years, why don’t I have values a lot higher like my HSV1 values? Are positive HSV2 IGG values typically lower than positive HSV1 IGG values for most individuals who are infected with both viruses?

yes, HSV 2 positive values are normally never as high as the HSV 1 scores.

Maybe I dont’t understand the confirmation inhibition assay test which I took on 1/31/23. As I mentioned, it provided 2 values.
1.39 for the HSV2 screening index
86.1 for % inhibition.
The 1.39 stated normal/in range which was highlighted in green almost seemed like it was conflicting from 86.1 score which stated abnormal highlighted in red.
Why was the 1.39 normal/in range? Normal/in-range for being positive?
With a 1.39 value, what % of false positives do you see at that level?

The 1.39 is positive, not negative. Anything over 1.1 is considered positive and Quest will sometimes do an inhibition assay if your provider ordered a confirmatory test. However, we’ve seen several people who’ve had positive inhibition assays and negative western blots

It does sound like a Western Blot will clarify a lot of information.
Yes, it would.

Terri

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