› Forums › Herpes Questions › Low positive then negative retest–long seroconversion period? › Reply To: Low positive then negative retest–long seroconversion period?
1) How would you interpret an initial IgG of 1.09 with a positive supplemental, followed by a 1.12 IgG with a negative supplemental? Was the first test likely a false positive? I’m wanting clarity so I know how to move forward with my partner, who is accepting either way.
I would say that an equivocal test result with a positive supplemental followed by a negative supplemental would indicate that the first is a false positive. I now have 117 patients who have positive supplemental with negative western blots.
2) Could the second test in December, the negative result, be an artifact of incomplete seroconversion? Or, stated differently, could it take 7 plus months to complete seroconversion for HSV-2?
I don’t think that is the case. We are seeing good agreement between people who get a negative supplemental test and, subsequently, a negative western blot.
I would do a WB, but I’m unemployed due to a #metoo issue at my last job. Do you have any info on defraying the cost for low-income people?
I am not aware of any help in defraying the cost of the western blot but I really do think the negative supplemental is very good news for you.