› Forums › Herpes Questions › Can IGG antibodies drop to negative levels if HSV-2 is latent long enough? › Reply To: Can IGG antibodies drop to negative levels if HSV-2 is latent long enough?
1) Peace of mind, I don’t want to worry about infecting my fiancée if I don’t have HSV-2.
There is a problem here and that is that you appear to have taken antiviral medicine almost ever since you first got infected or may have possibly been infected and the antiviral can impact the validity of the IgG or western blot test, causing a false negative as you appear to know. If you really want to know if you have HSV 2, you would need to come off antivirals for about 8 weeks (you were already off for a month at the beginning) for greatest accuracy. You could do the blot now and if you are positive, it’s a done deal but if you are negative, we cannot know because you decided to take daily Valtrex before you had a diagnosis through swab testing was done of symptoms or you waiting enough time to allow your body to make antibody. If you do come off antiviral medicine, you are surely aware that this would increase the risk of transmission to an infected partner.
2) I am in month 9 of a lawsuit against the woman who I believe infected me and will likely require confirmatory testing to ensure my blood tests weren’t false positives. I didn’t have sex for almost a year before exposure and after which I experienced severe symptoms indicative of a primary infection.
So just to be sure that I understand you’re suing someone for giving you herpes based on the IgG test of 1.66? I think you need more proof than what you have to win a lawsuit because at that index value, there is probably a 75-80% chance that this is a false positive. However, it could have gone
higher had you not been on antiviral medicine. That’s a very complicated situation to sort out because of your long dosing of antiviral medicine. Did you have any swab testing done with your initial symptoms that was positive?