Reply To: Anal HSV-1 › Forums › Herpes Questions › Anal HSV-1 › Reply To: Anal HSV-1 June 1, 2023 at 2:46 pm #81801 Terri WarrenKeymaster Yes, both locations (penis and anus) are in the same nerve group and when it is active in one location of your body it is often active in the other. Terri