Reply To: HSV-1 IGG Test Results & Confusion

[lotsofquestions123456789]

Western Blot Results from 6/2023:
HSV-1: Indeterminate
HSV-2: Negative

A quick recap of my HSV-1 IgG positive history (I had 6 negatives along the way – comprehensive history is above in original post):

Positive 12/2014 (1.77)
Positive 1/2023 (1.29)
Positive 5/2023 (1.76)

Since my most recent negative 5/2019, I kissed 3 girls (nothing more).

Girl 1: 11/2022
Girl 2: 1/2023 (this was after January positive)
Girl 3: 2/2023 (she tested negative IgG)

I read the reasons given for an indeterminate result. One being “during seroconversion” and patient history. But the explanation only explicitly mentions seroconversion time for HSV-2, not HSV-1 so I’m wondering if the same time frame applies to HSV-1.

I don’t want to sway any of your responses, but it seems to me if I was actually positive as far back as 2014, any seroconversion would have happened already.

But I also understand an infection could have occurred after that, which could have been from kissing Girl 1 in November 2022, but that was 7 months ago, plus that would not explain 2014 positive….

Questions:

1) What’s your professional opinion regarding the HSV-1 indeterminate result given my total history?

2) I have come this far and want to take this all the way. What’s the next step?

3) Should I have another WB performed at a later date? If so, when exactly?

In terms of exactly when the first test was performed, all I can tell from the results is that the sample was received 6/13/23.

Thank you!