For a female with a once ever GHSV1 outbreak (2.5 years ago) who has evidence of an intimate partner not becoming infected over several months…
Was that confirmed with antibody testing? If yes, then this suggests that you aren’t shedding often, which I would expect after being infected with GHSV1 for more than two years. Christine Johnston’s work suggest that at 2 years out from infection, people shed on about 4 days out of a year.
If on top of this, we were to use condoms exclusively as well as daily valtrex
That would reduce it but because it is so rare anyway, we don’t know by how much
I am also aware that not all ethnicities are equally vulnerable (i.e. esp non Caucasian) could this suggest not as easily to shed virus?
We don’t have any data to suggest that, no.
Finally, do we know by what age it is likely that most people seroconvert or what that chance is?
We don’t.
Are there any real chances of therapeutic vaccines that would eliminate risk of shedding?
oh yes, but the research is focusing on HSV 2 but we already know from preliminary results that it benefits HSV 1 as well, at least in one example.
Terri
oh yes, but the research will focus mostly on HSV 2