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Based on these results, I postulated I had a relatively newly acquired HSV2 and that the bump on my vulva was most likely HSV2; and had spread to (or simultaneously infected) my mouth.
9/22 Vulva bump pretty much gone, but mouth problems getting worse. Nothing on lips other than barely visible pinprick bumps on the left side, but tongue and entire roof of my mouth is sore. Over the next 10 or more days the sensitivity continues. Pieces of skin seem to be peeling off the roof of mouth. Geographic tongue fades, but there seem to be fissures on tongue. No classic looking cold sore emerges.
9/28 Final (10th) day of the high dose of Valtrex. I switch to 500 mg/day.
10/1 Mouth symptoms becoming increasingly worrisome. I have my PCP swab roof of my mouth for PCR test. Still awaiting results.
10/2 Recieve results of culture from the vaginal lesion. I am SHOCKED, because I was expecting the swab test to show up as HSV2 — or as nothing. Instead they were:
HSV Types 1+2 Culture (SP)
Result: Herpes Type1
10/7 Mouth symptoms continue, but have improved. Continue Valtrex 500mg/day
So, that’s my timeline. I’m quite confused by the positive culture for GHSV1 as well as my oral symptoms (which I’m guessing are OHSV1).
Some additional info:
20 years ago, a after making out with a guy (I can’t recall exactly what we did but it did not include oral or vaginal sex — I was still a virgin) I experienced for the first time some very unpleasant lip symptoms. They were pinprick bumps on my lips (the same as what I experienced this time, but they were worse). They were tingly/itchy and uncomfortable, but never blistered, scabbed, or took on appearance of a classic cold sore. Can’t recall symptoms inside my mouth like the ones I’m currently experiencing, but lip symptoms happened several times over next few years, each time more mild. Haven’t had anything like them in years. I always assumed it was OHSV1, though blood tests (though I didn’t have one for years after that initial incident) never showed anything.
I have a history of extremely elevated AntiNuclear Antibodies that have never been explained. Also Epstein Barr.
In August of this year I was extremely sick and took very high doses of antibiotics, which gave me candida problems (which I’m prone to), and probably wore down my immune system. Maybe even oral thrush.
I’d love to get your assessment. I’ve accepted I have GHSV1, but wondering if tests for HSV2 could be false positives.
-If I am positive for HSV2 we know, based history of blood tests, it’s a relatively new infection. Does it make sense that my only visible genital symptom since acquisition, were confirmed by culture as HSV1?
-Do my mouth symptoms (current or past) sound like HSV of either type? Would HSV be appearing this severely despite being on so much Valtrex (started before mouth symptoms even appeared? It’s been 17 days of these symptoms, all while on Valtrex!
-Given the severity of the oral symptoms, and the fact that i was swabbed positively for GHSV1 while HSV1 antibodies came back negative, could this be a primary G+OHSV1 OB? (This is confusing given my past history of mouth symptoms).
-If not a primary OB, why would all of this be happening now — exactly simultaneous to HSV2 antibodies being detected for the first time ever in my blood? Could recently acquired (asymptomatic) HSV2 trigger an HSV1OB?
-If the bumps I got years ago were HSV1 (I do think they were), and I was a virgin at the time of acquisition, could I suddenly have a genital lesion from the same infection after more than 20 years? Unless I autoinnoculated back then, I don’t see how that could be possible.
-What is the likelihood that my vagial swab culture was mistyped and the the genital lesion was actually HSV2?
-Do people who are positive for both HSV1&2 get simultaneous OBs of both, or are they more prone to alternate? (Could my mouth symptoms be HSV2, simultaneous to a genital HSV1 lesion? It doesn’t exactly make sense because mouth symptoms are so much more severe, and I know HSV2 doesn’t like the mouth).
-Could my history of elevated AntiNuclear antibodies and/or possibly newly acquired HSV1 somehow be triggering a false positive for HSV2 antibodies?
-One of my IgG scores is below the 3.5, and one is above, though they were drawn two days apart. Is it worth western blot?
Thank you so very much for all of your help Teri!! I am so grateful to have discovered you as a resource.