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I just now realized my subscription had to be renewed, and I had asked another question, sort of over the three previous posts. If you’d be so kind, could you just look at the three posts before this one, they all go together, and give me your opinion? And thank you!
Guess I should have waited for the test results before the two previous posts, but it came back negative, and here’s what it says:
Test Name In Range Out Of Range Reference Range Lab
HSV 2 IGG INHIBITION, IA EZ
HSV 2 IGG SCREENING INDEX <0.90
The HSV-2 IgG screening assay was repeated on a
different platform as part of the inhibition test,
and the result was negative; thus the Inhibition result
could not be determined. Most samples exhibiting this
type of discrepancy have initial HSV-2 IgG index values
of 1.10-3.00. If early HSV-2 infection is suspected,
submission of another sample collected 2-3 weeks after
this sample is recommended.
% inhibition <60 NEGATIVE
% inhibition > or = 60 POSITIVE
This assay is intended only for samples giving a
positive index in the HSV-2 type-specific IgG
screening assay which is repeated as part of the
inhibition assay. A POSITIVE inhibition
interpretation indicates true HSV-2 specific
reactivity, whereas a NEGATIVE inhibition
interpretation suggests that the positive screening
index is falsely positive.
It’s not the WB, but with my previous low positives, and this, I’m going to assume I can call it a day on this, yes?
Just to add, the code( I believe) for this one, is 37529 and on the order it says: HSV-2 IgG Inhibition IA (Serum)
Hello again Terri. I just did another full std panel, which obviously includes the HSV 2 IGG test. Positive again, with 1.31, so now it’s
4/7/2020 – 1.35
5/19/2020 – 1.44
3/1/2022 – 1.37
10/7/2023 – 1.31
I pretty much expected a positive again, and still feel it’s a false positive, like you said, so not super worried. BUT, this time, the online service I used, recommended what they call a confirmatory test, to ‘end the debate’, or so they say. I asked them, and turns out is the ELISA test. I got locked out here, as couldn’t remember my password, and made too many attempts before using the lost password option, because I was going to ask your opinion. Anyway, I just went ahead and did it, and now I obviously have the password thing resolved, so my question is, did I just pretty much waste my time with that ‘confirmatory’ test, because when I did a little research, it seems like it’s not considered super reliable. I know they wanted to sell another test, but they must have some reason to believe this ends the debate, but super curious what your opinion is. If it come back negative, I’ll call it a day, because my IFF results point to a false positive, but if it comes back positive, I won’t be sure what to think. Almost seems like I’d be back in that same ‘false positive’ neighborhood. If positive, maybe just for the piece of mind, I will figure out some way to get the WB test. Zip codes is 95482, but probably nothing has changed. The woman at this place said the ELISA is the next best thing to the WB, maybe that’s true.
Well, on my original post in this thread, I had stated that since the WB,which was negative, back when you could just do it at Quest, I had a couple full panels, both all negative, then after this new sexual partner, whom I only performed oral sex on, my ocd told me to get another full panel, and it was that low positive, with another 6 weeks later, then this one. I know I had a false positive a long time ago, which prompted me to get the WB, which came back negative. Again, no symptoms. Had I not had a newer partner at some point, I wouldn’t have done it. Now it’s in my head.
Can I ask…..let’s say a person is truly negative, can they go back and forth with this IGG test, and have say, 2 negatives in a row, then 3 low positives, or whatever combo. Hope that made sense. I know you once said I will probably always test low positive with this test, but just wonder if a negative pops up once in a while.
Also, let’s say I wanted to cut to the chase, and try the WB again, would I simply call local labs outside of Quest and Labcorp, and tell them I want to do the WB, and I need blood drawn, spun up, and essentially handed back to me?
Thanks in advance!
Hello again Terri,
So….just for the heck of it, I did another HSV 2 IGG test, almost 2 years since my last one, that the consensus was most likely false positive. Since I don’t have easy access to the Western Blot test in or near zip code 95482, I went with that, and might add, no symptoms either.
That said, this new HSV 2 IGG test was 1.37, so now it’s
4/7/2020 – 1.35
5/19/2020 – 1.44
3/1/2022 – 1.37
In your opinion, does that put an exclamation point on what you said previously, in that this is most likely a false positive? And, correct me if I’m wrong, if 2 years ago, it really was positive, wouldn’t that number have gone up by now?
Oh, and is Quest still not drawing the blood, or doing the tests? Just checking.
Thanks in advance!
- This reply was modified 1 year, 11 months ago by acillatem.
Hi Terri. So, I did another IgG HSV2 test, 6 weeks after the first test, and it came back 1.44. Although slightly higher, and correct me if I’m wrong, still very low, especially now that it’s just about 19 weeks.So, 90 days after encounter in question, 1.35. 6 weeks after that, 1.44. No symptoms. I feel this is like you said, a second very low positive, and very likely another false positive, curious what you think. Wouldn’t that number be significantly higher by now, if a true positive?
Thanks for the reply Terry. Yes, I do believe the previous Western Blot was due to a low positive HSV 2 result. I seem to remember 1.40 something.
I could check with the person, and see if they’re willing to test.
I know I got a couple full std panels since the Western Blot, and previous to this last panel, which prompted me to come here, and didn’t have a positive at all for HSV 2, but I guess that doesn’t mean this one is accurate, like you said.
I will consider the Western Blot, but sure wish it was as easy as last time. Oh well…..it is what it is.
All that said, if I do another IgG at 6 weeks, and say it’s very close to the same low number, or perhaps even equivocal or negative, would kit be fairly safe to assume I’m negative? And by the same token, if the number has gone up a fair amount, would it mean I’m more likely positive, or would it still be just as likely a false positive. Unless the number was much higher, or?? I know there’s no definitive answer, but guess just wondering the likelihood. I know you get where I’m going with this. With the lack of simplicity of doing the western blot, the “low” risk activity I engaged in, and no symptoms, and that 1.35, could I do one or two more IgG tests, and come to a reasonable conclusion? I’m over explaining, you get it. And of course, it would be your professional opinion, that I respect, and nothing I’d hold you to, haha.
- This reply was modified 3 years, 10 months ago by acillatem.