Forum Replies Created
Thank u for ur reply. Terri
Currently, my plan is to take the final IgG test at 12 weeks out and, if the result is negative, I am going to move on.
My worst fear is that I get another equivocal or low positive result at the final test at out. I think that is still a likely event even though I am not infected, right? Then, I will do the blot. (Even though the final result is negative, I may seek for the blot for the peace of mind.) Does it sound reasonable?
I think I have to work with u, but it seems that u are very busy person. So, I want to know how long should one wait to have a video conference with u these days? Also, could you give me an information on the lab in DC area that draws, spins and ships the blood for blot (you told me you know one)?
Against your advice, I took a retest at 9 weeks out because I could not handle my anxiety well.
The result was negative for HSV 1 & 2. Again, the test was done by LabCorp.
Here is the summary of the events.
Last sexual encounter : unprotected oral and virginal sex with a woman whose STD status is unknown.
4 weeks out : HSV 1 < 0.90 Negative, HSV 2 1.05 Equivocal (Quest)
6 weeks out : HSV 2 < 0.91 Negative (LabCorp)
9 weeks out : HSV 1 < 0.91 Negative, HSV 2 < 0.91 Negative (LabCorp)
The following are my questions.
1. What is the chance of seroconversion between 9 and 12 weeks? How likely do you think that I am infected? Have you ever seen a case with a similar degree of risk factor (risky but one-time encounter) and the presentation of symptoms (no symptoms) in which the test result was negative until 9 weeks but turned out positive later?
2. I know that the maximum sensitivity of the IgG test (92% for HSV 2 and 70% for HSV 1). Aside from my anxiety issue, would you strongly advise against if I choose to forget about everything and move on with the current results? Would you still insist that I should get a retest at 12 weeks?
3. For the first test, I had to visit Quest Lab twice because they said the first sample was problematic. Given that, do you think that poor handling of the sample can be a cause for the wrong test result? Or is it possible that the first result was just an error not because of some protein?p
4. As you can notice, I change the lab from Quest to LabCorp for the follow up tests. I know that their tests are similar type (ELISA) but not the same one. Also, I found inconsistency between these two labs in your forum. Do u think that there is significant difference between two labs or one is better than the other? Should I be concerned by my choice of labs for the past tests? Should I have stick to the same labs?
I am not entirely sure whether I can move on, but I really want to move on.
- This reply was modified 11 months, 3 weeks ago by pgsm2019.
Even though it is more likely that I am not infected, I have been under extreme anxiety because of a concern regarding seroconversion.
So, I keep looking into my genital area to see if there is anything that looks like HSV. I thin there have been none.
But, last Saturday, I noticed small white patches (or spots) under my glans. So, it’s been almost a week. It seems that they got slightly bigger. When the skin of that part (under my glans) was folded (I am circumcised), I barely notice slight decoloration. But when I stretch that skin, they look like small white patches. They are not like bumps and do not contain any liquid. There is no sensation associated with it. No burning, no tingling, no itchiness. There is no redness around the patches. Based on the info that I found online, they do not seem related to HSV. DO they sound like Herpes to you?
Also, because of an extreme anxiety that I am going through, I am thinking about getting a retest (IgG blood test, it is 9 weeks out). And I will put all the concern to bet if the result is negative. Does it sound reasonable to you? Or should I still get a test at 12 weeks out?
If the result falls in low positive, I would get Western Blot. But I want to get it as soon as possible. It is ok to get Western Blot at 10 weeks out? Or should I wait until 12 weeks out?
Also, since I got an equivocal result once before, I am also very scared to get a retest though it is the only thing I can do. Do u think that it is likely for me to get another equivocal result because of some protein in my blood that is not HSV antibody even though I were not infected?
Finally, based on your clinical experience, do u think that I am infected or not? I know that you can only guess. If there were no equivocal result in the first place, I would have never thought about this virus. But, because of it, I am in a lot of mental pain.
I will wait for ur reply. Thank you.
Thank you for your answer, Terri
I know that I do not have a good reason to believe that I am infected by HSV2 at this point, but am still concerned about the first equivocal result.
The question like ‘why did I get an equivocal test result in the first place if I were not infected?’ does not leave from my head.
Also, as I said in the above, I have symptoms like frequent urination, feeling of residual urine after an urination, lower back pain, and little bit of itchiness at the tip of my penis.
I am familiar with all the above symptoms because I have had chronic prostatitis for around 15 years, but still sometimes those symptoms concern me because they got a bit worse in the past couple of weeks.
Also, I examine my genital area very closely every time I go to the bathroom. Yesterday, some of the blood vessels on my testicle seemed slightly inflated and, today, I found out that some area on my testicles are a little bit white (maybe too dry). But I have had no blisters, bumps, or sores so fat.
I think I am being too paranoid.
Though, I want to ask
1. it is ok to think that the first equivocal result does not have much meaning since the test is sometimes erratic and the next result was negative?
2. do any of the above descriptions of my symptoms (or observations) sound like HSV 2?
I know that this is the last post of my subscription, but want to hear your opinion on my concerns because I think I am overly concerned.
At 6 weeks, I got a retest.
The test was HSV 2 type-specific AB IgG with reflex done by Labcorp.
The test result was Negative (<0.91). A specific index value was not provided.
Given this additional info, how would evaluate the chance of me being negative (not infected)? (I am 37 male with no major health issue)
Do you think I need to know the specific index value from this test?
Also, regarding the transmission, could you evaluate the prob of transmitting virus with numerical values (of course, approximately) if I were infected through an unprotected sex with no meds at all?
Also, are there any factors that you think may affect the test result such as fasting, drinking alcohol or other meds except for taking antivirals?
Finally, are there any factors that you know may affect the pace of developing antibodies such as age, meds, or other diseases?
I will wait for your reply.